Breakthrough in Chronic Myeloid Leukemia research

photo courtesy: CBS News

Researchers at the University of Iowa's College of Medicine are developing a treatment that could possibly eliminate Chronic Myeloid Leukemia or CML.

Researchers found two drugs, prostaglandin E1 (PGE1) and misoprostol, reduced and eliminated leukemia stem cells in a tested mouse model.

Researchers extracted CML from patients and injected mice with cancer.

"We think it's going to be good," said Hai-Hui (Howard) Xue, MD, Ph.D., UI professor of microbiology and immunology. "That between this drug and the conventional drug to actually bring a cure to CML."

"The real exciting aspect of Howard's work is that it suggests that the use of a drug that's commonly used to treat things like ulcers could be used to treat this form of leukemia," explains Steven Lentz, MD, Steven Lentz, MD, Ph.D. Director of Hematology.

Next, researchers are designing a clinical trial to test on humans.

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